Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438107 | 0.87 | ELANE (0.41) | SRD5A2ELANE | |
| SCHEMBL8605131 | 0.87 | ELANE (0.41) | ELANEKMT2APKMRXRARXRB | |
| SCHEMBL8605725 | 0.87 | ELANE (0.41) | ELANEKMT2APKMRXRARXRB | |
| SCHEMBL3036136 | 0.76 | KMT2A (0.49) | KMT2AMAPK1 | |
| SCHEMBL7429786 | 0.73 | ELANE (0.43) | SRD5A2ELANERXRARXRB | |
| SCHEMBL6430665 | 0.72 | CA12 (0.36) | ELANEKMT2A | |
| SCHEMBL7371447 | 0.72 | CA12 (0.36) | ELANEKMT2A | |
| SCHEMBL7406495 | 0.70 | ALDH1A1 (0.51) | MAPK1 | |
| SCHEMBL7368608 | 0.70 | NPC1 (0.35) | — | |
| Benzoic Acid SCHEMBL28384787 | 0.69 | DAO (0.58) | SRD5A2MAPK1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808056-A | Process for preparing substituted azetidinones | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0858460-A1 | PROCESS FOR PREPARING SUBSTITUTED AZETIDINONES | Merck & Co., Inc. (US) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997016448-A1 | PROCESS FOR PREPARING SUBSTITUTED AZETIDINONES | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |