Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434188 | 0.88 | ELANE (0.43) | ELANESRD5A2ALDH1A1HPGDABCC4 | |
| SCHEMBL7439317 | 0.88 | ELANE (0.43) | ELANESRD5A2ALDH1A1HPGDABCC4 | |
| SCHEMBL7422689 | 0.87 | SRD5A1 (0.37) | ELANESRD5A2 | |
| SCHEMBL7428859 | 0.78 | ALDH1A1 (0.51) | ALOX5ALDH1A1HPGD | |
| SCHEMBL8775291 | 0.78 | ALDH1A1 (0.51) | ALOX5ALDH1A1HPGD | |
| SCHEMBL9193358 | 0.76 | CYP4F2 (0.42) | ELANEALDH1A1MAPTLMNAGAA | |
| SCHEMBL7429922 | 0.71 | MEN1 (0.38) | ALDH1A1MAPTHPGDGAATSHR | |
| SCHEMBL11795064 | 0.69 | F2 (0.56) | FFAR1ALOX5ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL27574680 | 0.68 | F2 (0.55) | FFAR1ALOX5ALDH1A1MAPTHPGD | |
| SCHEMBL8605132 | 0.66 | KDM4E (0.42) | ALDH1A1MAPTHPGDCYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481671-A1 | New substituted azetidinones as anti-inflammatory and antidegenerative agents | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |