Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735969 | 0.85 | CA12 (0.72) | HDAC2HDAC3HDAC1NCOR2DRD2 | |
| SCHEMBL6657027 | 0.84 | HDAC2 (0.67) | HDAC2HDAC3HDAC1NCOR2HTR2C | |
| SCHEMBL6657894 | 0.83 | NHERF1 (0.69) | HDAC2HDAC3HDAC1NCOR2DRD2 | |
| SCHEMBL6655159 | 0.83 | LMNA (0.63) | HDAC2HDAC3HDAC1NCOR2HTR2C | |
| SCHEMBL25003661 | 0.83 | KDM4E (0.57) | HDAC2HDAC3HDAC1NCOR2HTR2C | |
| SCHEMBL6656151 | 0.82 | HDAC2 (0.62) | HDAC2HDAC3HDAC1NCOR2HTR2C | |
| SCHEMBL13587037 | 0.81 | HDAC2 (0.67) | HDAC2HDAC3HDAC1NCOR2HTR2C | |
| SCHEMBL12584537 | 0.81 | NAMPT (0.72) | HDAC2HDAC3HDAC1NCOR2HTR2C | |
| SCHEMBL4930492 | 0.81 | HDAC2 (0.70) | HDAC2HDAC3HDAC1NCOR2KDM4E | |
| SCHEMBL18641772 | 0.81 | HDAC2 (0.60) | HDAC2HDAC3HDAC1NCOR2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |