Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.51 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113906 | 0.81 | MRGPRX4 (0.50) | MRGPRX4PPIABRD4MAOBPTGER1 | |
| SCHEMBL16097496 | 0.79 | LMNA (0.51) | PPIABRD4LMNAKDM4ENPC1 | |
| SCHEMBL15561368 | 0.78 | MAOB (0.54) | MRGPRX4PPIABRD4MAOBPTGER1 | |
| SCHEMBL28701031 | 0.78 | EPHX2 (0.46) | MRGPRX4TRPM4KDM4ENPC1MITF | |
| SCHEMBL22897684 | 0.76 | TRPM4 (0.41) | MRGPRX4TRPM4KDM4ENPC1MITF | |
| SCHEMBL1647357 | 0.76 | FOLH1 (0.62) | MRGPRX4PPIAMAOBPTGER1KDM4E | |
| SCHEMBL8104076 | 0.75 | MRGPRX4 (0.50) | MRGPRX4PPIABRD4MAOBPTGER1 | |
| SCHEMBL9653543 | 0.75 | C5AR1 (0.59) | CYP19A1KDM4ENPC1MITFTHRB | |
| SCHEMBL7492629 | 0.74 | CXCR2 (0.62) | MRGPRX4TRPM4PPIABRD4MAOB | |
| SCHEMBL1646681 | 0.74 | MRGPRX4 (0.60) | MRGPRX4PPIAMAOBPTGER1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1367777-A | Benzenamine derivatives as anti-coagulants | BERLEX LAB (US) | 2002-09-04 | — | — | CN | disclosed |
| EP-1200405-A1 | BENZENAMINE DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 2002-05-02 | — | — | EP | disclosed |
| US-6350761-B1 | INHIBITORS OF THE ENZYME, FACTOR XA; | BERLEX LABORATORIES, INC. | 2002-02-26 | — | — | US | disclosed |
| WO-2001009093-A1 | BENZENAMINE DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 2001-02-08 | — | — | WO | disclosed |