Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113906 | 0.86 | MRGPRX4 (0.50) | MRGPRX4PTGER1BRD4PPIAPTGDR2 | |
| SCHEMBL4643473 | 0.83 | LRRK2 (0.49) | ALDH1A1PTGER1BRD4LMNAMEN1 | |
| SCHEMBL2897343 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1BRD4PPIAPPIDLTA4H | |
| SCHEMBL630140 | 0.76 | MEN1 (0.48) | MRGPRX4ALDH1A1MAOBPPIDLTA4H | |
| SCHEMBL31748463 | 0.76 | ALDH1A1 (0.47) | ALDH1A1PPIAPPIDLTA4HKDM4E | |
| SCHEMBL647879 | 0.76 | MRGPRX4 (0.40) | MRGPRX4BRD4LTA4HPDCD1CD274 | |
| SCHEMBL7422855 | 0.75 | MRGPRX4 (0.51) | MRGPRX4PTGER1BRD4PPIAPTGDR2 | |
| SCHEMBL15561368 | 0.75 | MAOB (0.54) | MRGPRX4PTGER1BRD4PPIAMAOB | |
| SCHEMBL6412094 | 0.74 | SMPD1 (0.54) | ALDH1A1MAOBKDM4ELMNAMEN1 | |
| SCHEMBL15595142 | 0.74 | LMNA (0.44) | ALDH1A1PPIAPPIDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |