Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 15/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 12/20 | 0.46 |
| ▸ | CASP6 | P55212 | 10/20 | 0.46 |
| ▸ | CASP1 | P29466 | 6/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL8414659 | 0.92 | CASP3 (0.58) | CASP3CASP8CASP6CASP1CASP7 | |
| Naphthalene SCHEMBL8412272 | 0.87 | CASP3 (0.51) | CASP3CASP8CASP6CASP1 | |
| Naphthalene SCHEMBL7419594 | 0.87 | CASP1 (0.50) | CASP3CASP1 | |
| SCHEMBL7417111 | 0.85 | CASP1 (0.59) | CASP3CASP8CASP6CASP1CASP7 | |
| Naphthalene SCHEMBL8410958 | 0.84 | CASP1 (0.44) | CASP3CASP8CASP6CASP1 | |
| Naphthalene SCHEMBL8414413 | 0.84 | CASP3 (0.50) | CASP3CASP8CASP6CASP1 | |
| SCHEMBL7422955 | 0.83 | CASP1 (0.64) | CASP3CASP8CASP6CASP1 | |
| Naphthalene SCHEMBL7414189 | 0.83 | CASP3 (0.51) | CASP3CASP8CASP6CASP1CASP7 | |
| Naphthalene SCHEMBL8055399 | 0.81 | CASP3 (0.45) | CASP3CASP8CASP6CASP1 | |
| Naphthalene SCHEMBL7417035 | 0.80 | CASP1 (0.49) | CASP3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001019373-A2 | METHODS AND COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |