Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MIF | P14174 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355121 | 0.85 | RAB9A (0.46) | RAB9ANPC1MAPTKDM4EMIF | |
| SCHEMBL6645546 | 0.79 | MAPT (0.39) | RAB9ANPC1MAPTKDM4EMIF | |
| SCHEMBL7944783 | 0.74 | GRM2 (0.44) | MAPTLMNAGRM2 | |
| SCHEMBL19153416 | 0.74 | AKT1 (0.43) | GRM2KDM1AHDAC8HDAC6 | |
| SCHEMBL3819098 | 0.74 | AKT1 (0.52) | RAB9ANPC1KMT2ALMNAMEN1 | |
| SCHEMBL12410847 | 0.73 | LOXL2 (0.50) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14838597 | 0.73 | NPC1 (0.40) | RAB9ANPC1MAPTKDM4EMIF | |
| SCHEMBL2637771 | 0.73 | NPC1 (0.40) | RAB9ANPC1MAPTKDM4EMIF | |
| SCHEMBL5846695 | 0.73 | HDAC1 (0.43) | GRM2KDM1AHDAC8HDAC6 | |
| SCHEMBL2637768 | 0.73 | NPC1 (0.40) | RAB9ANPC1MAPTKDM4EMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228854-B1 | 1-BENZAZEPINE DERIVATIVE ANTICOAGULANTS; STROKE PREVENTION | COR THERAPEUTICS, INC. | 2001-05-08 | — | — | US | disclosed |
| EP-0994894-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007731-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |