Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL744059 | 0.93 | HTR6 (0.41) | HTR6AKR1C3CYP3A4HTR2C | |
| Trifluoroacetic Acid SCHEMBL744053 | 0.89 | HTR6 (0.46) | HTR6CYP3A4HTR2CSETD7MLNR | |
| Trifluoroacetic Acid SCHEMBL741451 | 0.88 | HTR6 (0.39) | HTR6AKR1C3CYP3A4HTR2CHTR2A | |
| Trifluoroacetic Acid SCHEMBL743110 | 0.88 | HTR6 (0.41) | HTR6CYP3A4HTR2CHTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL744534 | 0.87 | HTR6 (0.43) | HTR6CYP3A4HTR2CHTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL743069 | 0.85 | HTR6 (0.49) | HTR6CYP3A4HTR2CHTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL743495 | 0.85 | HTR6 (0.47) | HTR6CYP3A4HTR2CHTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL741153 | 0.84 | HTR6 (0.52) | HTR6CYP3A4HTR2CHTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL743994 | 0.84 | HTR6 (0.46) | HTR6CYP3A4HTR2CHTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL743674 | 0.84 | HTR6 (0.41) | HTR6CYP3A4HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138333-B2 | Sulfonyl-indole derivatives | PROXIMAGEN LIMITED (GB) | 2012-03-20 | — | — | US | disclosed |
| US-20080293694-A1 | New compounds | BIOVITRUM AB (PUBL.) (SE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293694-A1 | New compounds | HTR6, HTR1A, HTR1B | HTR6 1/4885AKR1C3 515/4885CYP3A4 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.