Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995549 | 1.00 | CTSS (0.52) | CTSSCTSKCTSLMEN1ALDH1A1 | |
| SCHEMBL7418533 | 1.00 | CTSS (0.52) | CTSSCTSKCTSLMEN1ALDH1A1 | |
| SCHEMBL8995546 | 0.97 | CTSS (0.53) | CTSSCTSKCTSLMEN1ALDH1A1 | |
| SCHEMBL8995544 | 0.97 | CTSS (0.53) | CTSSCTSKCTSLMEN1ALDH1A1 | |
| SCHEMBL8995548 | 0.92 | CTSS (0.52) | CTSSCTSKCTSLCTSB | |
| SCHEMBL8995562 | 0.92 | CTSS (0.52) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7423272 | 0.92 | CTSS (0.52) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7423600 | 0.89 | CTSS (0.55) | CTSSCTSKCTSLMEN1ALDH1A1 | |
| SCHEMBL8995569 | 0.89 | CTSS (0.55) | CTSSCTSKCTSLMEN1ALDH1A1 | |
| SCHEMBL7423594 | 0.89 | CTSS (0.55) | CTSSCTSKCTSLMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |