Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.52 |
| ▸ | CTSL | P07711 | 8/20 | 0.52 |
| ▸ | CTSB | P07858 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995562 | 1.00 | CTSS (0.52) | CTSSCTSLCTSBCTSKP2RX7 | |
| SCHEMBL7423272 | 1.00 | CTSS (0.52) | CTSSCTSLCTSBCTSKP2RX7 | |
| SCHEMBL8995549 | 0.92 | CTSS (0.52) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7423262 | 0.92 | CTSS (0.52) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7418533 | 0.92 | CTSS (0.52) | CTSSCTSLCTSBCTSK | |
| SCHEMBL8995544 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBCTSKP2RX7 | |
| SCHEMBL8995546 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBCTSKP2RX7 | |
| SCHEMBL8995535 | 0.88 | CTSS (0.46) | CTSSCTSLCTSBCTSK | |
| SCHEMBL8995530 | 0.88 | CTSS (0.46) | CTSSCTSLCTSBCTSK | |
| SCHEMBL22398518 | 0.87 | CTSL (0.54) | CTSSCTSLCTSBCTSKCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |