Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.48 |
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478100 | 0.83 | NLRP3 (0.45) | MEN1KMT2A | |
| SCHEMBL22113081 | 0.83 | NLRP3 (0.45) | MEN1KMT2A | |
| SCHEMBL2586006 | 0.83 | NLRP3 (0.45) | MEN1KMT2A | |
| SCHEMBL2502292 | 0.83 | NLRP3 (0.45) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28551850 | 0.82 | NLRP3 (0.44) | POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30655761 | 0.82 | NLRP3 (0.44) | POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3999288 | 0.82 | NLRP3 (0.44) | POLBMEN1KMT2A | |
| SCHEMBL16271273 | 0.79 | POLB (0.43) | POLBMEN1KMT2A | |
| SCHEMBL2152877 | 0.79 | POLB (0.43) | POLBMEN1KMT2A | |
| SCHEMBL30523454 | 0.79 | POLB (0.43) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801648-A4 | SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP INC (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0801648-A1 | SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5556909-A | PROTEOLYTIC ENZYME INHIBITOR, TREATMENT OF DEGENERATIVE DISEASES, SUCH AS EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS | SANOFI WINTHROP INC. (US) | 1996-09-17 | — | — | US | disclosed |
| WO-1996016951-A1 | SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-06-06 | — | — | WO | disclosed |