Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586006 | 1.00 | NLRP3 (0.45) | NLRP3KMT2AMEN1AKR1B1IDO1 | |
| SCHEMBL29478100 | 1.00 | NLRP3 (0.45) | NLRP3KMT2AMEN1AKR1B1IDO1 | |
| SCHEMBL22113081 | 1.00 | NLRP3 (0.45) | NLRP3KMT2AMEN1AKR1B1IDO1 | |
| Hydrochloric Acid SCHEMBL28551850 | 0.98 | NLRP3 (0.44) | NLRP3KMT2AMEN1AKR1B1IDO1 | |
| Hydrochloric Acid SCHEMBL3999288 | 0.98 | NLRP3 (0.44) | NLRP3KMT2AMEN1AKR1B1IDO1 | |
| Hydrochloric Acid SCHEMBL30655761 | 0.98 | NLRP3 (0.44) | NLRP3KMT2AMEN1AKR1B1IDO1 | |
| SCHEMBL30765055 | 0.84 | MEP1B (0.43) | NLRP3KMT2AMEN1NOS3NOS1 | |
| SCHEMBL10064650 | 0.84 | MEP1B (0.43) | NLRP3KMT2AMEN1NOS3NOS1 | |
| SCHEMBL27125027 | 0.84 | MEP1B (0.43) | NLRP3KMT2AMEN1NOS3NOS1 | |
| SCHEMBL23470803 | 0.84 | CA12 (0.45) | AKR1B1IDO1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132524-A1 | SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY | AVIKO RADIOPHARMACEUTICALS, LLC | 2024-04-25 | — | — | US | disclosed |
| WO-2024064210-A1 | SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY | AVIKO RADIOPHARMACEUTICALS, LLC (US) | 2024-03-28 | — | — | WO | disclosed |
| US-8030513-B2 | Rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| US-20100204376-A1 | Rheology Control Agents | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2010-08-12 | — | — | US | disclosed |
| US-7741510-B2 | Rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-22 | — | — | US | disclosed |
| EP-1838749-A1 | COATING COMPOSITIONS CONTAINING RHEOLOGY CONTROL AGENTS | E.I.Du pont de nemours and company (US) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006076715-A1 | COATING COMPOSITIONS CONTAINING RHEOLOGY CONTROL AGENTS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060155021-A1 | Coating compositions containing rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-07-13 | — | — | US | disclosed |
| US-20060155146-A1 | Rheology control agents | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155146-A1 | Rheology control agents | HCRTR1, HCRTR2, REL | NLRP3 3037/4885KMT2A 2284/4885MEN1 4191/4885 |
| US-20100204376-A1 | Rheology Control Agents | HCRTR1, HCRTR2, REL | NLRP3 3037/4885KMT2A 2284/4885MEN1 4191/4885 |
| US-20240132524-A1 | SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY | NME2, BTD, BLVRB | NLRP3 4825/4885KMT2A 3293/4885MEN1 1136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.