Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423444 | 1.00 | ARG1 (0.40) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| SCHEMBL7423438 | 1.00 | ARG1 (0.40) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| SCHEMBL9602233 | 0.84 | ARG1 (0.43) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| SCHEMBL27434842 | 0.82 | GRIN2D (0.41) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| SCHEMBL6194188 | 0.82 | GRIN2D (0.41) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| SCHEMBL9602127 | 0.81 | GRIN2D (0.40) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6194183 | 0.81 | CYP1A2 (0.40) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL28632967 | 0.78 | ARG1 (0.36) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| SCHEMBL9808318 | 0.77 | THRB (0.45) | ARG1DRD3SLC6A3ALDH1A1MEN1 | |
| SCHEMBL9808316 | 0.77 | THRB (0.45) | ARG1DRD3SLC6A3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |