Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423089 | 0.89 | ADORA2A (0.39) | ADORA2AADORA2B | |
| SCHEMBL8000439 | 0.86 | ADORA2A (0.41) | ADORA2AADORA2B | |
| SCHEMBL5226057 | 0.86 | ADORA2A (0.56) | ADORA2AADORA2B | |
| SCHEMBL7274376 | 0.83 | ADORA2A (0.68) | ADORA2AADORA2B | |
| SCHEMBL7425894 | 0.83 | ADORA2A (0.53) | ADORA2AADORA2B | |
| SCHEMBL9706669 | 0.81 | ADORA2A (0.45) | ADORA2AADORA2B | |
| SCHEMBL7673623 | 0.80 | TLR7 (0.41) | ADORA2AADORA2B | |
| SCHEMBL7420292 | 0.80 | ADORA1 (0.44) | ADORA2AADORA2B | |
| SCHEMBL9788499 | 0.78 | KDM4E (0.33) | — | |
| SCHEMBL5231243 | 0.78 | PDE2A (0.46) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268373-B1 | ENZYME INHIBITORS | EURO-CELTIQUE S.A. (LU) | 2001-07-31 | — | — | US | disclosed |
| US-6025361-A | EFFECTIVE PDE IV INHIBITORS, ASTHMA | EURO-CELTIQUE, S.A. (LU) | 2000-02-15 | — | — | US | disclosed |
| US-5977119-A | Trisubstituted thioxanthines | EURO-CELTIQUE, S.A. (LU) | 1999-11-02 | — | — | US | disclosed |
| EP-0799040-A4 | TRISUBSTITUTED THIOXANTHINES | EURO CELTIQUE SA (LU) | 1998-04-01 | — | — | EP | disclosed |
| EP-0799040-A1 | TRISUBSTITUTED THIOXANTHINES | Euroceltique S.A. (LU) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996018400-A1 | TRISUBSTITUTED THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | disclosed |