Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.56 |
| ▸ | PYGL | P06737 | 18/20 | 0.55 |
| ▸ | PYGM | P11217 | 17/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799483 | 1.00 | SCN9A (0.56) | SCN9APYGLPYGM | |
| SCHEMBL4799468 | 1.00 | SCN9A (0.56) | SCN9APYGLPYGM | |
| SCHEMBL12376317 | 0.89 | SCN9A (0.69) | SCN9APYGLPYGM | |
| SCHEMBL12376364 | 0.89 | SCN9A (0.69) | SCN9APYGLPYGM | |
| SCHEMBL5638220 | 0.89 | SCN9A (0.69) | SCN9APYGLPYGM | |
| SCHEMBL6763198 | 0.87 | AADAT (0.49) | SCN9APYGLPYGM | |
| SCHEMBL19207822 | 0.85 | SCN9A (0.47) | SCN9A | |
| SCHEMBL7819630 | 0.85 | SCN9A (0.47) | SCN9A | |
| SCHEMBL7421160 | 0.85 | SCN9A (0.48) | SCN9A | |
| SCHEMBL7418257 | 0.84 | PYGL (0.52) | SCN9APYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |