Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476752 | 0.81 | MAPK1 (0.54) | L3MBTL1MAPK1PKMCSNK1DHTT | |
| SCHEMBL7363701 | 0.75 | HDAC3 (0.49) | L3MBTL1MAPK1PKMCSNK1DHDAC3 | |
| SCHEMBL10730213 | 0.75 | MAPK1 (0.51) | L3MBTL1MAPK1PKMHPGDCYP1A2 | |
| SCHEMBL7423663 | 0.73 | L3MBTL1 (0.65) | L3MBTL1MAPK1CSNK1DHPGDCYP1A2 | |
| SCHEMBL2856934 | 0.73 | HPGD (0.56) | MAPK1PKMCSNK1DHPGDCYP1A2 | |
| SCHEMBL10764124 | 0.73 | MAPK1 (0.52) | L3MBTL1MAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL10972900 | 0.72 | MAPK1 (0.60) | L3MBTL1MAPK1CSNK1DHPGDCYP1A2 | |
| SCHEMBL402775 | 0.72 | HPGD (0.55) | L3MBTL1MAPK1PKMCSNK1DHPGD | |
| SCHEMBL10757211 | 0.72 | MAPK1 (0.51) | L3MBTL1MAPK1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL10757208 | 0.72 | MAPK1 (0.51) | L3MBTL1MAPK1CSNK1DHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |