Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419779 | 0.83 | MAPK1 (0.58) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7419774 | 0.83 | MAPK1 (0.58) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7359506 | 0.81 | MAPK1 (0.58) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7359502 | 0.81 | MAPK1 (0.58) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| Bromide SCHEMBL7418359 | 0.80 | MAPK1 (0.57) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| Bromide SCHEMBL7418358 | 0.80 | MAPK1 (0.57) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7639974 | 0.79 | MAPT (0.72) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7428589 | 0.75 | L3MBTL1 (0.60) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| SCHEMBL20023020 | 0.75 | L3MBTL1 (0.70) | L3MBTL1MAPK1CYP1A2CYP2C19KMT2A | |
| SCHEMBL1555297 | 0.75 | ALDH1A1 (0.57) | L3MBTL1MAPK1CYP1A2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |