Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365088 | 0.83 | HRH3 (0.55) | LMNAKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL6947975 | 0.81 | HRH3 (0.52) | LMNAKMT2ATDP1RAB9AALDH1A1 | |
| SCHEMBL20612118 | 0.80 | RAB9A (0.48) | LMNARAB9AALDH1A1NPC1HPGD | |
| SCHEMBL24848155 | 0.79 | KMT2A (0.69) | LMNAKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL8479941 | 0.78 | GABRA1 (0.47) | LMNARAB9AALDH1A1NPC1FLT3 | |
| SCHEMBL15876112 | 0.78 | GRIN2D (0.58) | LMNAKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL7425507 | 0.77 | SRD5A2 (0.48) | LMNATDP1RAB9AALDH1A1NPC1 | |
| SCHEMBL21101013 | 0.77 | KDM4E (0.46) | LMNAKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL6512775 | 0.77 | HRH3 (0.71) | LMNAKMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL30741601 | 0.76 | IDO1 (0.61) | LMNAKMT2ASLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |