Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.64 |
| ▸ | PDE4A | P27815 | 6/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.64 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418078 | 0.78 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7422584 | 0.78 | PDE4A (0.73) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7423419 | 0.77 | PDE4A (0.68) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7423546 | 0.77 | PDE4A (1.00) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7422190 | 0.76 | PDE4A (0.81) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7413548 | 0.74 | PDE4A (1.00) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7423896 | 0.73 | PDE4A (1.00) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7418801 | 0.73 | PDE4A (0.64) | PDE4DPDE4APDE4BPDE4CDRD2 | |
| SCHEMBL7417274 | 0.69 | PDE4A (0.55) | PDE4DPDE4APDE4BPDE4CAVPR1B | |
| SCHEMBL7421632 | 0.69 | PDE4A (0.67) | PDE4DPDE4APDE4BPDE4CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |