Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415292 | 0.96 | NPC1 (0.39) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7420260 | 0.92 | F2 (0.39) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7452481 | 0.92 | F2 (0.39) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7411197 | 0.91 | F2 (0.35) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7419831 | 0.90 | F2 (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7415098 | 0.88 | RAB9A (0.41) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7417541 | 0.87 | F2 (0.39) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7447260 | 0.87 | F2 (0.41) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7418783 | 0.87 | F2 (0.46) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7450699 | 0.86 | F2 (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244636-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | Boehringer Ingelheim Pharma KG (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047896-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |