Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424207 | 1.00 | LMNA (0.38) | LMNAHPGD | |
| SCHEMBL11114124 | 0.89 | ACE (0.35) | — | |
| SCHEMBL11114123 | 0.89 | ACE (0.35) | — | |
| SCHEMBL11111840 | 0.88 | ACE (0.35) | — | |
| SCHEMBL11111836 | 0.88 | ACE (0.35) | — | |
| SCHEMBL11104772 | 0.86 | LMNA (0.38) | LMNAHPGD | |
| SCHEMBL11104778 | 0.86 | LMNA (0.38) | LMNAHPGD | |
| SCHEMBL7424244 | 0.83 | ACE (0.35) | — | |
| SCHEMBL11108991 | 0.83 | MEN1 (0.36) | LMNAHPGD | |
| SCHEMBL11129894 | 0.81 | ENO1 (0.39) | LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | claimed |
| US-4460579-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1984-07-17 | — | — | US | claimed |
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |
| US-4460579-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1984-07-17 | — | — | US | disclosed |