Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369636 | 0.96 | AVPR2 (0.46) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL8639834 | 0.89 | AVPR2 (0.52) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL7480359 | 0.88 | NPC1 (0.38) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL8662244 | 0.88 | AVPR2 (0.47) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL7374737 | 0.87 | KCNA5 (0.40) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL7347547 | 0.87 | CYP1A2 (0.46) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL7966792 | 0.86 | HPGD (0.42) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL7751032 | 0.86 | HPGD (0.52) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL7346621 | 0.86 | MEN1 (0.43) | AVPR2AVPR1AMEN1KMT2AHPGD | |
| SCHEMBL7345676 | 0.86 | KMT2A (0.43) | AVPR2AVPR1AMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |