Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424282 | 0.88 | AVPR2 (0.49) | NPC1AVPR2AVPR1AALDH1A1POLB | |
| SCHEMBL8008767 | 0.87 | POLB (0.36) | NPC1ALDH1A1POLBMEN1HPGD | |
| SCHEMBL7998651 | 0.87 | ALDH1A1 (0.34) | NPC1AVPR2AVPR1AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL8022968 | 0.86 | NPC1 (0.42) | NPC1MEN1HPGDKMT2AKDM4E | |
| SCHEMBL7476628 | 0.86 | POLB (0.35) | ALDH1A1POLBMEN1HPGDKMT2A | |
| SCHEMBL8509973 | 0.85 | AVPR2 (0.39) | AVPR2AVPR1A | |
| SCHEMBL8010692 | 0.84 | ALDH1A1 (0.42) | NPC1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7369636 | 0.84 | AVPR2 (0.46) | NPC1AVPR2AVPR1AALDH1A1POLB | |
| SCHEMBL8010702 | 0.84 | ALDH1A1 (0.41) | NPC1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7967025 | 0.81 | MAPT (0.39) | ALDH1A1KDM4ESMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |