Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.42 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | KLK1 | P06870 | 4/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.36 |
| ▸ | F9 | P00740 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102488 | 0.81 | F2 (0.65) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7102495 | 0.81 | F2 (0.65) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7450241 | 0.79 | F2 (0.57) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7442317 | 0.76 | F2 (0.54) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7422210 | 0.76 | F2 (0.40) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7453719 | 0.75 | F2 (0.42) | F2F10PLGKLK1KLK5 | |
| SCHEMBL6455724 | 0.75 | F2 (0.39) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7225527 | 0.74 | F2 (0.46) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL6451890 | 0.72 | F2 (0.60) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7097353 | 0.72 | F2 (0.53) | F2F10PLGKLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244636-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | Boehringer Ingelheim Pharma KG (DE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047896-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | claimed |