Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 9/20 | 0.56 |
| ▸ | ACE | P12821 | 8/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434816 | 1.00 | FKBP1A (0.56) | FKBP1AACECTRB1MMEL1ACE2 | |
| SCHEMBL10404568 | 0.89 | ACE (0.53) | FKBP1AACECTRB1 | |
| SCHEMBL6438368 | 0.87 | ACE (0.58) | ACEACE2 | |
| SCHEMBL6438372 | 0.87 | ACE (0.58) | ACEACE2 | |
| SCHEMBL8378226 | 0.87 | ACE (0.58) | ACEACE2 | |
| SCHEMBL6439093 | 0.86 | ACE (0.62) | FKBP1AACECTRB1ACE2 | |
| SCHEMBL6436340 | 0.82 | ACE (0.59) | FKBP1AACEMMEL1ACE2 | |
| SCHEMBL7426069 | 0.82 | ACE (0.59) | FKBP1AACEMMEL1ACE2 | |
| SCHEMBL7148899 | 0.82 | ACE (0.63) | FKBP1AACE | |
| SCHEMBL7537159 | 0.82 | ACE (0.63) | FKBP1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |