Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422961 | 0.93 | ITGA4 (0.49) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6744314 | 0.87 | ITGA4 (0.44) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7423777 | 0.84 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6741881 | 0.81 | ITGA4 (0.51) | ITGB1ITGA4 | |
| SCHEMBL6741878 | 0.81 | ITGA4 (0.51) | ITGB1ITGA4 | |
| SCHEMBL6741932 | 0.81 | ITGA4 (0.49) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6742321 | 0.81 | ITGB1 (0.50) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6739377 | 0.81 | ITGB1 (0.50) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6744901 | 0.80 | ITGA4 (0.49) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6744310 | 0.79 | ITGA4 (0.48) | ITGB1ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089989-A1 | INHIBITORS OF ALPHA4BETA1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067230-A1 | INHIBITORS OF α4β1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-29 | — | — | WO | disclosed |