Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | ITGB1 | P05556 | 18/20 | 0.78 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.78 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.78 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.78 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.65 |
| ▸ | ITGAL | P20701 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066390 | 0.90 | L3MBTL1 (0.69) | L3MBTL1ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL7432342 | 0.89 | L3MBTL1 (0.64) | L3MBTL1ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL6641625 | 0.88 | ITGB1 (1.00) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL480284 | 0.88 | ITGB1 (1.00) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL14802063 | 0.88 | ITGB1 (1.00) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL6638294 | 0.87 | ITGB1 (0.98) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL18608870 | 0.86 | ITGB1 (0.77) | L3MBTL1ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL7538961 | 0.86 | ITGB1 (0.73) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL13726570 | 0.85 | ITGA4 (0.72) | L3MBTL1ITGB1ITGA4ITGB7ITGA2 | |
| Alcohol SCHEMBL6829612 | 0.85 | ITGB1 (0.94) | ITGB1ITGA4ITGB7ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005445-A1 | N-ALKANOYLPHENYLALANINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010312-A1 | N-ALKANOYLPHENYLALANINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-04 | — | — | WO | disclosed |