Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418735 | 0.89 | PYGL (0.54) | CCKBRACEPYGL | |
| SCHEMBL4797202 | 0.88 | PYGL (0.55) | CCKBRPYGL | |
| SCHEMBL7421751 | 0.88 | PYGL (0.52) | CCKBRACEPYGL | |
| SCHEMBL4797181 | 0.88 | PYGL (0.55) | CCKBRPYGL | |
| SCHEMBL7421660 | 0.87 | ACE (0.57) | CCKBRACEPYGL | |
| SCHEMBL7420473 | 0.86 | ACE (0.48) | CCKBRACEPYGL | |
| SCHEMBL7421160 | 0.86 | SCN9A (0.48) | CCKBRACE | |
| SCHEMBL7421536 | 0.84 | PYGL (0.55) | CCKBRACEPYGL | |
| SCHEMBL7421691 | 0.83 | CCKBR (0.51) | CCKBR | |
| SCHEMBL7418257 | 0.83 | PYGL (0.52) | CCKBRPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |