Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774658 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRTP53HSD17B10STAT3 | |
| SCHEMBL742471 | 0.78 | CCNE1 (0.45) | SMN1; SMN2TSHRTP53CDK1HTT | |
| SCHEMBL741057 | 0.77 | PIN1 (0.56) | SMN1; SMN2TSHRHSD17B10CXCR2CDK1 | |
| SCHEMBL30411673 | 0.74 | SMN1; SMN2 (0.80) | SMN1; SMN2TSHRTP53HSD17B10HTT | |
| SCHEMBL4924809 | 0.74 | SMN1; SMN2 (0.80) | SMN1; SMN2TSHRTP53HSD17B10HTT | |
| Chloroform SCHEMBL743258 | 0.74 | PIN1 (0.53) | SMN1; SMN2TSHRHSD17B10CXCR2CDK1 | |
| SCHEMBL30523415 | 0.72 | HSD17B10 (0.69) | SMN1; SMN2TSHRTP53HSD17B10STAT3 | |
| SCHEMBL16146326 | 0.72 | HSD17B10 (0.69) | SMN1; SMN2TSHRTP53HSD17B10STAT3 | |
| SCHEMBL3907002 | 0.70 | CDK1 (0.48) | TSHRHSD17B10STAT3IP6K1CXCR2 | |
| SCHEMBL16146477 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRTP53HSD17B10STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430036-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130233-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2010-11-18 | — | — | WO | disclosed |