Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.45 |
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740877 | 0.84 | CCNE1 (0.39) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL743587 | 0.79 | ADORA3 (0.60) | TSHRADORA2AADORA3NFKB1TP53 | |
| SCHEMBL743586 | 0.79 | ADORA3 (0.60) | TSHRADORA2AADORA3NFKB1TP53 | |
| SCHEMBL742472 | 0.78 | SMN1; SMN2 (0.48) | CDK2MAPTHTTALDH1A1MEN1 | |
| SCHEMBL786075 | 0.76 | YTHDC1 (0.62) | CCNE1CDK2MAPTHTTMEN1 | |
| SCHEMBL774658 | 0.75 | SMN1; SMN2 (0.53) | CDK2MAPTHTTALDH1A1MEN1 | |
| SCHEMBL786909 | 0.73 | CCNE1 (0.61) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL15117694 | 0.72 | FLT3 (0.59) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL15117550 | 0.72 | CDK2 (0.51) | CCNE1CDK2CCNT1CCNT2CCNE2 | |
| SCHEMBL786378 | 0.71 | YTHDC1 (0.57) | CCNE1CDK2CCNT1CCNT2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430036-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130233-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2010-11-18 | — | — | WO | disclosed |