Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382102 | 0.71 | SLC1A3 (0.34) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL28789567 | 0.67 | EPOR (0.34) | EPOR | |
| SCHEMBL23986454 | 0.66 | CHRNB2 (0.41) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL27014703 | 0.65 | CA1 (0.43) | KDM4CKDM4APHF8KDM2A | |
| SCHEMBL16393836 | 0.65 | KMT2A (0.46) | EPORLMNATP53NPSR1 | |
| SCHEMBL28488965 | 0.65 | GPR84 (0.36) | KDM4CKDM4APHF8 | |
| SCHEMBL306435 | 0.64 | CA12 (0.37) | — | |
| SCHEMBL304559 | 0.64 | MC4R (0.35) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL27588072 | 0.64 | — | — | |
| SCHEMBL14826530 | 0.64 | TSHR (0.34) | EPORLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |