Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422145 | 0.91 | GRIK1 (0.40) | MMP2MMP13MMP3GRIK1GRIK2 | |
| SCHEMBL7421531 | 0.89 | MMP13 (0.41) | MMP2MMP13MMP3ACACBGRIK1 | |
| SCHEMBL8271393 | 0.71 | CYP1A2 (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3872212 | 0.70 | L3MBTL1 (0.43) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL1609861 | 0.70 | L3MBTL1 (0.43) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL2247539 | 0.70 | L3MBTL1 (0.43) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL1610132 | 0.70 | L3MBTL1 (0.43) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL18302853 | 0.68 | SLC1A1 (0.41) | MEN1KMT2A | |
| SCHEMBL18302851 | 0.68 | SLC1A1 (0.41) | MEN1KMT2A | |
| SCHEMBL11127558 | 0.67 | MEN1 (0.44) | MMP2MMP13MMP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944587-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2002-03-20 | — | — | EP | disclosed |
| EP-0944587-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998024759-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |