Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 7/20 | 0.35 |
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | PROC | P04070 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417913 | 1.00 | SIRT2 (0.35) | SIRT2SIRT1F10F2PROC | |
| SCHEMBL8029146 | 0.88 | SIRT2 (0.35) | SIRT2SIRT1F10F2PROC | |
| SCHEMBL8042725 | 0.88 | SIRT2 (0.35) | SIRT2SIRT1F10F2PROC | |
| SCHEMBL8039167 | 0.87 | HCRTR1 (0.39) | SIRT2SIRT1F10F2DPP4 | |
| SCHEMBL7423151 | 0.84 | KDM4E (0.35) | F10F2PROCPRSS1PLG | |
| SCHEMBL7424077 | 0.84 | KDM4E (0.35) | F10F2PROCPRSS1PLG | |
| Hydrochloric Acid SCHEMBL8040100 | 0.83 | KDM4E (0.35) | F10F2PROCPRSS1PLG | |
| Hydrochloric Acid SCHEMBL7423721 | 0.83 | KDM4E (0.35) | F10F2PROCPRSS1PLG | |
| SCHEMBL27461354 | 0.82 | KDM4E (0.34) | F10F2PROCPRSS1PLG | |
| SCHEMBL7424934 | 0.82 | FNTA (0.44) | DPP4FNTAFNTBPGGT1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034093-A | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-03-07 | — | — | US | disclosed |