Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425275 | 0.84 | SYK (0.53) | SYKBCL2MAOBPTPN1HDAC1 | |
| SCHEMBL6163742 | 0.80 | PTPN1 (0.57) | SYKBCL2MAOBPTPN1HDAC1 | |
| SCHEMBL7428462 | 0.78 | SYK (0.50) | SYKALOX5L3MBTL1HDAC1LTA4H | |
| SCHEMBL596575 | 0.78 | HDAC1 (0.67) | MAOBHDAC1 | |
| SCHEMBL1553476 | 0.78 | SYK (0.54) | SYKALOX5BCL2MAOBHDAC1 | |
| SCHEMBL271479 | 0.77 | CYP3A4 (0.56) | SYKALOX5BCL2MAOBPTPN1 | |
| SCHEMBL271480 | 0.77 | CYP3A4 (0.56) | SYKALOX5BCL2MAOBPTPN1 | |
| SCHEMBL7425238 | 0.77 | CYP3A4 (0.54) | SYKALOX5BCL2MAOBPTPN1 | |
| SCHEMBL7425236 | 0.77 | CYP3A4 (0.54) | SYKALOX5BCL2MAOBPTPN1 | |
| SCHEMBL30771411 | 0.77 | SYK (0.53) | SYKALOX5BCL2MAOBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006559-A1 | REDUCED DIPEPTIDE ANALOGUES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |