Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 6/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.47 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425275 | 0.84 | SYK (0.53) | PTPN1BCL2SYKMAOBHDAC1 | |
| SCHEMBL7425243 | 0.80 | SYK (0.51) | PTPN1BCL2SYKPSMB1PSMB10 | |
| SCHEMBL5525418 | 0.79 | CTSS (0.55) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL28302648 | 0.79 | SYK (0.55) | PTPN1CTSSCTSKBCL2SYK | |
| SCHEMBL596575 | 0.79 | HDAC1 (0.67) | MAOBHDAC1 | |
| SCHEMBL1553476 | 0.79 | SYK (0.54) | BCL2SYKMAOBHDAC1 | |
| SCHEMBL193474 | 0.79 | PTPN1 (0.73) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL2891538 | 0.79 | PTPN1 (0.73) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL193473 | 0.79 | PTPN1 (0.73) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL5888112 | 0.79 | PTPN1 (0.59) | PTPN1CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499588-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093234-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |