Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515391 | 0.79 | HPGD (0.67) | SMN1; SMN2RAB9ANPC1EPHX2HDAC2 | |
| SCHEMBL2955651 | 0.79 | PPARD (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1NAMPT | |
| SCHEMBL9602529 | 0.76 | HRH1 (0.41) | SMN1; SMN2 | |
| SCHEMBL12313360 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9ANPC1EPHX2HDAC2 | |
| SCHEMBL7423549 | 0.75 | EPHX2 (0.53) | SMN1; SMN2RAB9ANPC1EPHX2HDAC2 | |
| SCHEMBL27447850 | 0.74 | EPHX2 (0.58) | SMN1; SMN2RAB9ANPC1EPHX2HDAC2 | |
| SCHEMBL8918862 | 0.74 | NAAA (0.56) | SMN1; SMN2RAB9ANPC1EPHX2HDAC2 | |
| SCHEMBL2189223 | 0.74 | HSD17B10 (0.63) | SMN1; SMN2RAB9ANPC1EPHX2HDAC2 | |
| SCHEMBL20543214 | 0.74 | HSD17B10 (0.63) | SMN1; SMN2RAB9ANPC1EPHX2HDAC2 | |
| SCHEMBL16363845 | 0.73 | HDAC3 (0.57) | HDAC2HDAC8HDAC6HPGDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |