⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862294 | 0.79 | KIF11 (0.31) | — | |
| SCHEMBL16400085 | 0.78 | KIF11 (0.34) | — | |
| SCHEMBL7422830 | 0.77 | — | — | |
| SCHEMBL2390259 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL27790900 | 0.77 | — | — | |
| SCHEMBL27633572 | 0.77 | PDK2 (0.33) | — | |
| SCHEMBL29074274 | 0.77 | — | — | |
| Methane SCHEMBL27924248 | 0.77 | — | — | |
| SCHEMBL27607086 | 0.76 | — | — | |
| SCHEMBL28440789 | 0.75 | NPC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206843-A | Compounds for modulating proprotein convertase subtilisin/Kexin type 9(PCSK9) | SRX心脏有限责任公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-101296892-A | PPAR active compounds | PLEXXIKON INC (US) | 2008-10-29 | — | — | CN | disclosed |
| CN-1582287-A | Thiophenylthiopyrane dioxides as MMP or TNF-alpha inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-02-16 | — | — | CN | disclosed |
| CN-1157376-C | Arylpiperidinopropanol and arylpiperazinopropanol derivatives and drugs containing the same | ��һ��������ҩ��ʽ���� | 2004-07-14 | — | — | CN | disclosed |
| CN-1246110-A | Arylpiperidinopropanol and arylpiperazinopropanol derivatives and drugs containing the same | SUNTORY LTD (JP) | 2000-03-01 | — | — | CN | disclosed |
| EP-0958280-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999023072-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-05-14 | — | — | WO | disclosed |