Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP5 | P51878 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 3/20 | 0.44 |
| ▸ | CTSD | P07339 | 5/20 | 0.44 |
| ▸ | CTSE | P14091 | 5/20 | 0.44 |
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384686 | 0.91 | ADORA3 (0.63) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7384687 | 0.91 | ADORA3 (0.63) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7388547 | 0.90 | ADORA3 (0.64) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7419686 | 0.90 | ADORA3 (0.64) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7419420 | 0.90 | ADORA3 (0.64) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2771668 | 0.90 | ADORA3 (0.64) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7339738 | 0.90 | ADORA3 (0.64) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7415770 | 0.89 | ADORA3 (0.52) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7422194 | 0.88 | CTRB1 (0.52) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7417474 | 0.88 | CTRB1 (0.52) | RENADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |