Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429478 | 0.82 | KDM4E (0.61) | MEN1KMT2APOLBDCTPP1ALDH1A1 | |
| SCHEMBL5864193 | 0.78 | MEN1 (0.88) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL23555539 | 0.77 | MEN1 (0.47) | MEN1KMT2APOLBDCTPP1ALDH1A1 | |
| SCHEMBL7985041 | 0.76 | KMT2A (0.53) | MEN1KMT2APOLBALDH1A1SRC | |
| SCHEMBL2315638 | 0.75 | MEN1 (0.83) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7968478 | 0.75 | KMT2A (0.53) | MEN1KMT2APOLBDCTPP1SRC | |
| SCHEMBL7978416 | 0.75 | MEN1 (0.48) | MEN1KMT2APOLBDCTPP1ALDH1A1 | |
| SCHEMBL23555543 | 0.74 | MEN1 (0.46) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7428683 | 0.73 | BRPF1 (0.52) | ALDH1A1 | |
| SCHEMBL7353014 | 0.73 | MAPT (0.52) | MEN1KMT2ADCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |