Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 5/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | BRD1 | O95696 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.46 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.46 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.46 |
| ▸ | ATIC | P31939 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CDC25A | P30304 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7984525 | 0.83 | F2 (0.58) | APPHDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL7981601 | 0.78 | BRPF1 (0.51) | BRPF1SMARCA2BRD1BRD4BRD9 | |
| SCHEMBL7479090 | 0.77 | BRPF1 (0.52) | BRPF1SMARCA2BRD1BRD4BRD9 | |
| SCHEMBL7429478 | 0.77 | KDM4E (0.61) | APPHDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8028568 | 0.77 | F2 (0.61) | BRPF1SMARCA2ARCDC25ACDC25B | |
| Hydrochloric Acid SCHEMBL7981561 | 0.76 | F2 (0.57) | HDAC1HDAC2HDAC11HDAC8HDAC6 | |
| SCHEMBL7977900 | 0.74 | ATIC (0.66) | BRPF1SMARCA2BRD1BRD4ATIC | |
| SCHEMBL7981348 | 0.74 | BRPF1 (0.56) | BRPF1SMARCA2BRD1BRD4BRD9 | |
| SCHEMBL8026550 | 0.74 | F2 (0.73) | BRPF1SMARCA2BRD1BRD4BRD9 | |
| SCHEMBL7425922 | 0.73 | MEN1 (0.67) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |