Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382674 | 0.90 | ITGB1 (0.64) | ITGB1ITGA4KMT2AMEN1 | |
| SCHEMBL7389797 | 0.90 | ITGB1 (0.55) | ITGB1ITGA4KMT2AKDM4EALDH1A1 | |
| SCHEMBL5701051 | 0.89 | ITGB1 (0.69) | ITGB1ITGA4KMT2AKDM4EALDH1A1 | |
| SCHEMBL5700971 | 0.89 | ITGB1 (0.69) | ITGB1ITGA4KMT2AKDM4EALDH1A1 | |
| SCHEMBL7426550 | 0.89 | ITGA4 (0.64) | ITGB1ITGA4KMT2AMEN1 | |
| SCHEMBL7423658 | 0.88 | ITGB1 (0.65) | ITGB1ITGA4KMT2AMEN1 | |
| SCHEMBL7384591 | 0.88 | ITGA4 (0.61) | ITGB1ITGA4KMT2AMEN1 | |
| SCHEMBL7583142 | 0.87 | ITGA4 (0.60) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7383435 | 0.87 | ITGA4 (0.46) | ITGB1ITGA4ALDH1A1MAPTGAA | |
| SCHEMBL7651159 | 0.87 | ITGB1 (0.64) | ITGB1ITGA4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |