Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991482 | 0.82 | LMNA (0.41) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL7441255 | 0.75 | CYP2D6 (0.44) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7434948 | 0.70 | LMNA (0.51) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL7440773 | 0.69 | CA1 (0.50) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL10832049 | 0.69 | LMNA (0.50) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL10852007 | 0.69 | LMNA (0.40) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL7439179 | 0.65 | MAPT (0.43) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL10832911 | 0.64 | LMNA (0.57) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL11440969 | 0.64 | LMNA (0.50) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL7434736 | 0.64 | LMNA (0.50) | LMNAMAPTSMN1; SMN2NPSR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |