Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | KLK1 | P06870 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431443 | 0.82 | KLKB1 (0.44) | KLKB1ROCK1KLK1MAP4K1 | |
| SCHEMBL15955605 | 0.74 | NPC1 (0.55) | HDAC1HDAC6HPGDRAB9A | |
| SCHEMBL7702471 | 0.73 | F2 (0.42) | KLKB1F10KLK1HPGDF2 | |
| SCHEMBL1189517 | 0.73 | NPC1 (0.57) | HDAC1HDAC6RAB9A | |
| SCHEMBL6439089 | 0.72 | F2 (0.50) | KLKB1F10F2PRSS1 | |
| SCHEMBL27201339 | 0.70 | RAB9A (0.52) | KLKB1KLK1HPGDRAB9A | |
| SCHEMBL30885298 | 0.70 | RAB9A (0.52) | KLKB1KLK1HPGDRAB9A | |
| SCHEMBL6983681 | 0.67 | F2 (0.42) | F10HPGDF2 | |
| SCHEMBL6983215 | 0.66 | PLAU (0.60) | KLKB1ROCK1PRSS1 | |
| SCHEMBL6982094 | 0.66 | ROCK1 (0.53) | KLKB1ROCK1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |