Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 4/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708347 | 0.84 | KLKB1 (0.41) | F2PRSS1KLKB1F11MAP4K1 | |
| SCHEMBL6439089 | 0.78 | F2 (0.50) | F2PRSS1F10KLKB1 | |
| SCHEMBL15153143 | 0.77 | CHRM1 (0.46) | DPP7HPGDTSHRGAA | |
| SCHEMBL15153161 | 0.77 | CHRM1 (0.46) | DPP7HPGDTSHRGAA | |
| SCHEMBL15110037 | 0.75 | TSHR (0.42) | DPP7HPGDTSHRGAA | |
| SCHEMBL7425958 | 0.73 | HDAC1 (0.42) | F2PRSS1F10KLKB1HPGD | |
| SCHEMBL6437958 | 0.69 | F2 (0.53) | F2PRSS1KLKB1F11KLK1 | |
| SCHEMBL4704282 | 0.68 | CHRM1 (0.44) | TSHR | |
| Hydrochloric Acid SCHEMBL6435932 | 0.67 | PKM (0.49) | — | |
| SCHEMBL30885298 | 0.66 | RAB9A (0.52) | KLKB1HPGDKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444672-B1 | ORAL BIOVAILABILITY; INHIBITORS OF THROMBIN AND/OR FACTOR XA; SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2002-09-03 | — | — | US | disclosed |