Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | ALPL | P05186 | 8/20 | 0.65 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212110 | 0.88 | ALPL (0.70) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8752463 | 0.83 | CA12 (1.00) | KMT2ACA12CA9ALDH1A1LMNA | |
| SCHEMBL644500 | 0.79 | ALPL (1.00) | KMT2AALDH1A1GAAALPL | |
| SCHEMBL13539338 | 0.79 | ALPL (1.00) | ALDH1A1GAAALPL | |
| SCHEMBL31371215 | 0.78 | ALPL (1.00) | ALDH1A1LMNAGAAALPL | |
| SCHEMBL15211944 | 0.78 | ALPL (1.00) | ALDH1A1LMNAGAAALPL | |
| SCHEMBL1404336 | 0.78 | ALPL (1.00) | KMT2AALDH1A1GAAALPL | |
| SCHEMBL7425436 | 0.78 | PKM (0.82) | KMT2AALDH1A1HTTSMN1; SMN2PKM | |
| SCHEMBL15212129 | 0.78 | ALPL (1.00) | ALDH1A1GAAALPL | |
| SCHEMBL15211895 | 0.77 | ALPL (1.00) | ALDH1A1GAAALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |