Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426156 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7435483 | 0.93 | NOD1 (0.47) | ITGB3ITGA2BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7435481 | 0.93 | NOD1 (0.47) | ITGB3ITGA2BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7386699 | 0.93 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7386697 | 0.93 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7446059 | 0.93 | ITGB3 (0.44) | ITGB3ITGA2BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7446054 | 0.93 | ITGB3 (0.44) | ITGB3ITGA2BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7389172 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7389175 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7398729 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BSMN1; SMN2ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |