Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 14/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340577 | 0.87 | HTR7 (0.70) | HTR7ALDH1A1POLBHTR1AADRA2A | |
| SCHEMBL6337236 | 0.86 | HTR7 (0.68) | HTR7ALDH1A1POLBHTR1AADRA2A | |
| SCHEMBL6338842 | 0.80 | POLB (0.80) | HTR7POLBHTR1AADRA2AHTR6 | |
| SCHEMBL9895010 | 0.79 | HTR7 (0.65) | HTR7ALDH1A1POLBHTR1AADRA2A | |
| SCHEMBL6341348 | 0.79 | POLB (0.74) | HTR7POLBHTR1AADRA2AHTR6 | |
| SCHEMBL24069077 | 0.77 | HTR7 (0.87) | HTR7ALDH1A1POLBHTR1AADRA2A | |
| SCHEMBL25758471 | 0.75 | HTR7 (0.60) | HTR7ALDH1A1POLBHTR1AADRA2A | |
| SCHEMBL25284446 | 0.74 | HTR7 (0.72) | HTR7POLBHTR1AADRA2AHTR6 | |
| SCHEMBL25248038 | 0.74 | HTR7 (0.63) | HTR7ALDH1A1POLBHTR1AADRA2A | |
| SCHEMBL10194535 | 0.72 | POLB (0.74) | HTR7POLBHTR1AADRA2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000003987-A1 | 1,4-DIHYDROPYRIDINES AS CALCIUM BLOCKERS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |