Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165671 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL8932220 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL1165670 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7443327 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL1869047 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL5472460 | 0.82 | DHFR (0.79) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL5472464 | 0.82 | DHFR (0.79) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL13848400 | 0.81 | MAPT (1.00) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7438862 | 0.81 | MAPT (0.61) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7438873 | 0.81 | MAPT (0.61) | MAPTMEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639789-A | ANTITHROMBOTIC DRUGS | TANABE SEIYAKU CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0563798-B1 | Butadiene derivatives, their preparation and use as an antithrombotic agent | TANABE SEIYAKU CO (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5514815-A | ANTITHROMBOTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0563798-A1 | Butadiene derivatives, their preparation and use as an antithrombotic agent | TANABE SEIYAKU CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |