Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31585831 | 0.89 | CA12 (0.50) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL15326189 | 0.89 | CA12 (0.50) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL140846 | 0.80 | GAA (0.62) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL1184918 | 0.80 | ALDH1A1 (0.66) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL9398149 | 0.80 | GAA (0.66) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL1277539 | 0.79 | CA12 (0.44) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL1957013 | 0.79 | SLC6A4 (0.46) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| Ammonia Solution, Strong SCHEMBL18151874 | 0.79 | GAA (0.60) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL7101138 | 0.79 | GAA (0.60) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL5735678 | 0.79 | PTPRC (0.44) | KDM4EGAAALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068417-A3 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | SLASSI ABDELMALIK (CA) | 2002-11-14 | — | — | WO | disclosed |