Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426492 | 0.89 | ENPP2 (0.39) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL6181693 | 0.81 | HDAC3 (0.43) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL7651961 | 0.74 | CTSS (0.47) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL6181689 | 0.74 | CTSS (0.47) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL7426500 | 0.73 | HDAC3 (0.44) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL10810738 | 0.63 | HDAC3 (0.58) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| Bromide SCHEMBL10753066 | 0.62 | HDAC3 (0.57) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL4346128 | 0.62 | MEN1 (0.47) | ENPP2MAPTHTTMEN1KMT2A | |
| SCHEMBL11148430 | 0.59 | HDAC3 (0.70) | ENPP2MAPTHTTSMN1; SMN2KDM4E | |
| Bromide SCHEMBL10726966 | 0.58 | HDAC3 (0.69) | ENPP2MAPTHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |